Medicinal Chemist Resume

Title
Medicinal Chemist

Primary Skills
Please see resume for skills

Location
US-NY-New York (will consider relocating)

Posted
Feb-08-10


Objective: As a senior manager, I provide a positive impact on your product pipeline through extensive research and development experience, particularly in drug discovery (medicinal chemistry).

Profile: A very creative problem solver and highly effective 360 degree team player with a track record that has led to the discovery of several drug development candidates. Key issues solved include the oral absorption of renin inhibitors for treating hypertension, emetic effects and blood-brain barrier penetration effects of PDE4 inhibitors for treating asthma, inflammation or memory loss and whole blood potency of 5-LO inhibitors for treating asthma, inflammation or atherosclerosis. Pharmacokinetics, pharmacodynamics, distribution, formulation, metabolism and off target activity such as Herg and Pgp (transporters) are key areas of focus.

Computer Skills: MS Word, Excel, PowerPoint, Outlook, CS ChemDraw, ELN, IsisDraw, IsisBase, SciFinder, Crossfire, Waters Millenium, Micromass.

Professional Experience:
Drug Discovery Consultant Eliapharma Services Inc. 2009-present
Senior Research Fellow Merck Frosst Canada Ltd. 2000-2008
Research Fellow Merck Frosst Canada Ltd. 1993-2000
Senior Research Chemist Merck Frosst Canada Ltd. 1989-1993

Working with a team of scientists, discovered several drug development candidates for the treatment of Asthma, Chronic Obstructive Pulmonary Disease, Cardiovascular Diseases and Alzheimer Disease. As team member, Singulair for the treatment of asthma was discovered and brought to market. Recent notable achievement was the discovery of Merck's first clinical phosphodiesterase-4 inhibitor L-454,560 which has clinical efficacy for the treatment of asthma.

Education:
1987-1989 The Ohio State University, Columbus, Ohio
NSERC Postdoctoral Fellow, Professor Leo A. Paquette
Total Synthesis of (+)-Ikarugamycin

1987 University of Ottawa, Ottawa, Ontario
Ph.D., Synthetic Organic Chemistry, Professor Tony Durst
Synthesis of Podophyllotoxin and Analogs

1983 University of Toronto, Toronto, Ontario
B.Sc. with major in Chemistry, Professor G.H. Schmid
The effect of Environment on the Reactions of Thiiranium
Ions

Professional Development: Leadership Effectiveness Training, Managerial Grid, ACS Technical Writing Workshop, ACS Pharmacology for Chemists, Introduction to Molecular Biology and Background for Biotechnology, Immunology, Pharmacokinetics.


Professional Honors: NSERC Postdoctoral Fellowship 1987-1989
NSERC Postgraduate Scholarship 1985-1987



Certifications
See above


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